This means the trinket does nothing if your active item isn't fully charged, Single-use active items are consumed as normal, Doors can be opened without using up a key, However, when entering the door you are taken to a blue womb room with enemies to defeat. The charge direction now allows for a minor amount of control, * headless horseman, headless horsemen, red, grey, gray, A bag of bombs that will drop a bomb pickup every 2 rooms, UNLOCK: Unlock this item by beating Satan with Cain, * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, If used in a room with no enemies, Dark Esau will instantly spawn, Will chain up to two targets if you have Car Battery, if only one valid target is present it will be chained for twice the duration, UNLOCK: Unlock this item by defeating Delirium as Tainted Jacob, Rerolls all pedestal items, lowering all their internal item IDs by 1, For example: Brimstone's ID = 118, so it would be rerolled into Dead Bird (ID = 117), Sad Onion (ID = 1) will reroll into nothing, There are some gaps in item IDs which are skipped if no item exists, or will reroll into unexpected items if hidden items are present at that ID. Can fire tears but is immune to damage, Tainted Eden - Items taken before Birthright no longer get rerolled when taking damage, Tainted Lost - Grants an extra life. Pressing it again allows you to throw it at enemies. In exchange it gives you +0.05 Speed Up and Damage Up for every half a heart this item removes, The amount of Damage Up is (0.15 * FullHeartsRemoved ^ 2), If Isaac is already at half a red heart when stabbed, no damage or speed increases are given, The damage from being stabbed can be avoided with invincibility, however no damage or speed stat increases are gained if you do, Your individual tears each gain a random effect from either: Poison, Fear, Slow, Freeze, Charm, Burning, Homing, Bleeding, x2 Damage or Reduced damage, Allows you to walk on harmful floor effects without taking damage (e.g. 1 = poop, 2 = penny, 3 = bomb, 4 = key, 5 = red heart, 6 = pill, 7 = card, 8 = soul heart, 9 = gold heart, 10 = gold key, 11 = gold bomb, At the full 12 charges, a completely random effect will happen. Recharge Time: 6 rooms. UNLOCK: Unlock this item by defeating Delirium in The Void floor as The Forgotten, A passive item that puts a yellow ring around Isaac. REPENTANCE - Kidney Bean now has a bigger effect radius, no longer deals damage to the enemies it's charming, and charge time has been reduced to 1 (from 2). ), and much much more! Isaac starts with this item after it is unlocked. Gives Isaac an orbital fly, that will rapidly charge around and deflect any incoming tears that would hit Isaac. Abel, UNLOCK: Unlock this trinket by defeating Isaac, ?? They also no longer block player attacks or get extinguished by them, UNLOCK: Unlock this item by donating 400 pennies to the Shop, Isaac can now pick up hearts while at full health, which will be stored in the Jar and can be spawned again using the spacebar, Soul hearts and black hearts cannot be stored, If used in a Black heart or Eternal heart super secret room, it will spawn the relevant heart, * shop room pool, shop item pool, the lost item pool, glass. During this time he can walk over enemies to mark them for death. Using this card will also open a pathway of red rooms back to the regular floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob, "May the darkness swallow all around you", When used, grants +1.5 Damage Up, turns your hearts to Bone hearts and the Spirit of the Night effect (Spectral tears and the ability to fly) for the current floor, Also gives the Curse of Darkness effect that can't be removed for the current floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lazarus, Creates a trapdoor to a guaranteed crawl space, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eden, When used, this copies the effect of the card, pill, rune, soul stone or active item you used most recently, UNLOCK: Unlock this card by defeating Mega Satan as Tainted Eden, Turns all pedestal items in the current room into rotating items, which cycle between the old item and a random new item every second, This allows you to effectively reroll items like with The D6, but choose the old item as well if you want, Tainted Isaac has this effect passively for all items, If you use more than one in the same room, each pedestal item will cycle through +1 random item, Items are chosen from the item pool related to the current item, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Isaac, When used, all enemies in the current room drop half a red heart that will disappear after 2 seconds if not picked up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Magdalene, When used, this Soul Stone creates Red rooms for every possible exit in the current room, Red outlines of doors appear where this Soul Stone will create exits for, See the Red Key item description for more information about these Red rooms behave, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Cain, Activates the Dark Arts item effect, which turns Isaac into a ghost for a few seconds. * item room, treasure room, item room pool, round, circle, white, REPENTANCE - Homing tears now target enemies much more reliably, * item room, treasure room, item room pool, grey, gray, bent, x1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier), Cricket's Head used to be known as Max's Head in the original game and was renamed for Rebirth, * crickets head, cricket head, item room, treasure room, item room pool, golden chest pool, gold chest pool, cat, dead, brown, pink, * item room, treasure room, item room pool, broken, mirror, cracked, grey, gray, silver, Gives you a very high tear rate in exchange for a big range down, * item room, treasure room, item room pool, mm sweet lemonade, urine, yellow, tear, drop, x1.5 times Damage Multiplier if you also have Book of Belial (Does not stack with Magic Mushroom or Cricket's Head multipliers), * item room, treasure room, item room pool, crown, thorns, brown, hat, A familiar which follows Isaac and shoots normal tears which do 3.5 damage, Counts as 1 of 3 familiar items needed towards the Conjoined transformation, REPENTANCE - Brother Bobby now has an increased rate of fire, * item room, treasure room, item room pool, devil pool, devil room pool, devil deal, purple, blue, dead, baby, A lot of fly enemies are no longer aggressive towards Isaac, Attack Fly, Dart Fly, Eternal Fly, and Ring Fly are transformed into a neutral black fly, Boom Fly, Red Boom Fly, Drowned Boom Fly move slower, but still deal contact damage, Moter, Level 2 Fly, Full Fly, Pooter, and Super Pooter move slower and deal no contact damage, Can only be obtained from the shell game in the arcade, Counts as 1 of 3 fly items needed towards the Beelzebub transformation. Sales can be randomly applied just like regular shops, The ladder disappears after leaving the starting room, even if you haven't used it yet, In Antibirth this was called Jacob's Ladder, which had to be renamed as Afterbirth+ already had an item with this name, UNLOCK: Unlock this item by defeating Isaac as Jacob & Esau, Permanently shows the location of the boss room on the map, After defeating the shown boss fight, this item will activate a use of the Sun card (full heal and map reveal), fully recharge your active item, remove curses from the floor, gives +3 Damage Up and +1 Luck up for the rest of the floor, Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped), In The Void floor it shows a random boss room, which isn't necessarily Delirium's room, Adds one extra secret room and one extra super secret room to each floor. Re-rolled items pick from the current room's item pool. It leaps at enemies, dealing contact damage and firing quad shots at them for the rest of the room, Each time you destroy a poop, this item will spawn 1-4 friendly Dip familiars that follow you, block shots and attack nearby enemies, Different poop types will spawn different types of Dip, each with their own effect, Golden poop dips can petrify enemies, turning them to gold for a few seconds. mario, cartridge, nes, grey, gray, orange, When used, rerolls each item you currently own into another item room pool item and any pedestal items and pickups in the room, Has the combined uses of the D4, D6 and D20, REPENTANCE - Full run reroll effects (such as D4) are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by beating Boss Rush with The Lost, * item room, treasure room, item room pool, deathstar, death star, dice pip, white, circle, sphere, When used, the D4 re-rolls each item you currently have into another random item from the same item pool, If you have an item with no room pool (e.g. Blood Bag) it will be rerolled into a random Item Room item, Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle, REPENTANCE - Full run reroll effects are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by blowing up 30 slot machines, * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange, When used, 'devolves' all enemies in the room which are currently alive into another weaker type of enemy, * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban, When used, copies the effect of the card you are currently holding without consuming it, The charge time of this item depends on the quality of the card you're holding, Using this with the ? (D20 effect), 3 Dot - Rerolls all pickups on the entire floor, 4 Dot - Rerolls all pedestal items on the floor. the eternal hearts that drop in angel themed super secret rooms, All heart drops from Ace of Hearts will be Black Hearts, UNLOCK: Unlock this item by beating Satan with Azazel, *, black, devil, pointy, daemons tail, demons tail, demon tail, Dying in a sacrifice room while holding this trinket will unlock The Lost character, After The Lost is unlocked, dying anywhere with this trinket will bring you back to life as The Lost and the trinket will be deleted, When playing as Tainted Lost, you don't swap to being regular Lost, it simply acts as an extra life, UNLOCK: Unlock this item by beating Dark Room with Isaac, Everytime you pick up a coin, you fart, inflicting poison damage to nearby enemies, Greatly increases the chance of coins dropping from poops, Tears now move forwards at right angles, shifting left and right across the room, Increases your range stat by +10.0 while held but due to the fire pattern, your tears travel a similar distance to normal, Your tears now whip across the room at a very high shot speed, Shot speed gives your tears more effective range, but doesn't increase your range stat directly, Has a 22.22% chance to respawn with 3 Soul hearts as Blue Baby when you die, UNLOCK: Unlock this item by beating Satan with Lazarus, Everytime Isaac takes damage, one blue fly will spawn, * , the lost item pool, green, red, bloody, dead, Isaac's tears have a chance to poison enemies, The poison effect leaves a damage over time, which deals 4 or 6 damage per tick, The chance to poison enemies is affected by your luck stat and at +18 Luck it will activate every time, Isaac now has a chance to make a spectral and piercing tear, The chance to fire a piercing tear is affected by your luck stat and at +18 Luck it will activate every time, While held, this trinket gives a random mushroom effect each room, Possible mushrooms include: Mini Mush, Odd Mushroom (Thin), Odd Mushroom (Thick), The Compass, *, ping, pong, paddle, grey, gray, mushroom, While at 1/2 a red heart of health, you gain a Little Steve familiar that follows you and shoots homing tears, REPENTANCE - Umbilical Cord now has a high chance to spawn a Gemini familiar for the room when Isaac takes damage. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost', If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway, UNLOCK: Unlock this item by beating the Chest with Eden, 80% of heart drops are replaced with keys, Hearts turn into black hearts where possible. Charge time increased to 4 (from 2), UNLOCK: Unlock this item by dying 100 times, * item room, treasure room, item room pool, grey, gray, Holding the active item button will deplete the charge bar. You can also try doing this in Big Picture Mode. You can release the enemy early by using it again, Tainted Jacob starts with this item. Holy Mantle is the ultimate defensive-based item. The damage formula of the bombs has changed from damage * 5 + 30 to damage * 10, UNLOCK: Unlock this item by beating Mom's Heart 9 times, * item room, treasure room, item room pool, baby, fetus, foetus, jar, white, pink, bug, dr fetus, Causes pickups on the floor move towards the player, Works across pits, but not through Key blocks, REPENTANCE - Magneto is now capable of opening chests from a small distance. While aggressive, Blood Puppy deals 7.5 damage and drops half a red heart for every 10 enemies it kills. Toxic Dips release a poison cloud when they move/die. . Can be negated with Black Candle, Bad Gas - Isaac farts, poisoning enemies around him, Bombs are key - Switches number of bombs and keys, Explosive Diarrhea - Spawns five live troll bombs behind Isaac, one per second, Full Health - Restores all your empty red heart containers, Health Down - -1 HP. Recharge Time: 6 rooms. You get a couple of seconds of invincibility to move away after, The main benefit of this Soul Stone is that it automatically activates if you die, meaning it is effectively an extra passive life while held, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lazarus, Activates the D6 and D20 effects, rerolling all items and pickups in the room. or the path they take (My Reflection, Tiny Planet etc. grey, gray, Gives the player an invulnerability effect which lasts for a 10 seconds, Can be used to get free hits on the Blood Donation machines and Devil Beggars, * library pool, library room, book room pool, item room, treasure room, item room pool, white, pink, Allows Isaac to walk over gaps with a width of one tile, * shop room pool, shop item pool, the lost item pool, brown, wooden, Heals half a heart after every 13 enemies killed, Works with the Keeper for restoring coin HP, * item room, treasure room, item room pool, the lost item pool, black, grey, gray, bat, All spacebar items can now be 'overcharged', allowing them to be charged up twice instead of once, The extra charges appear in yellow on top of the normal green bars, This item works with self-recharging items, * shop room pool, shop item pool, pink, purple, 15c items are reduced to 7c.

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